CHALLENGES AND TRENDS IN THE PREVENTION OF CARDIOVASCULAR SIDE EFFECTS IN CANCER THERAPIES: A BIBLIOMETRIC APPROACH

Abstract

The prolonged survival of cancer patients has highlighted a consequence that was, until recently, underestimated. Among the most frequent side effects are hypertension, arrhythmias, heart failure, and myocarditis. The present study aims to address the following questions: Can bibliometric analysis be used to evaluate trends in the scientific production related to cardiovascular prevention and side effects in cancer therapies? And can co-occurrence network analysis help identify the challenges in cardiovascular prevention and adverse effects associated with cancer treatments? To answer these questions, a bibliometric study based on co-occurrence network analysis was conducted. The evaluated corpus comprised 159 scientific articles. The results allowed for the identification of four highly relevant clusters: Cluster 1: Natural Compounds and Alternative Oncoprotective Therapies; Cluster 2: Oncological Hormonal Therapies and Associated Systemic Risks; Cluster 3: Cardioprotective Strategies and Risk Management in Cancer Patients; and Cluster 4: Advanced Diagnostics and Biomarkers in Preventive Cardio-Oncology. These findings contribute new avenues of knowledge, enabling researchers interested in this field to explore novel constructs and apply advanced factorial models.

Palabras claves: Prevención cardiovascular, efectos secundarios, terapias contra el cáncer, bibliometría, Python