NUTRITIONAL STATUS & ITS RELATIONSHIP WITH BLOOD GLUCOSE LEVELS AND SEXUAL DYSFUNCTION IN DIABETIC ADULT MALE

Abstract

Background Malnutrition is a common problem in India. Malnourished patients may be more prone to a higher level of glucose levels and sexual dysfunction. The present study has been carried out to evaluate the nutritional status of diabetic patients and the association between malnutrition, glucose levels and sexual dysfunction problem of diabetic patients.

Objective: To explore the nutritional status and its relationship with blood glucose levels and sexual dysfunction among young diabetic male

Material & Methods: A prospective, cross-sectional study has been carried including 282 subjects between 25-60 years of age groups (married male) who were enrolled in the study,   patients visiting PGIMER, Chandigarh Endocrinology OPD. All patients were enrolled on prescribed proforma. Interview based data collection was done. Through clinical examination was done. Nutritional status was classified on the Mini Nutritional Assessment score. Sexual dysfunction assess by the International Index of Erectile Function (IIEF) Scale. Blood samples were obtained for blood glucose levels and HbA1c. Statistical calculation was done using SPSS 20.0.  P-value <0.05 was considered statically significant.

Results: Out of 282 participant’s prevalence of risk of malnutrition & normal nutrition status were 114 (40.4%) & 168 (59.6%) respectively. The sample mean ±SD Fasting Blood Glucose Level (FBG), Post Prandial Blood Glucose Level (PPBG), HbA1c & International Index of Erectile Function (IIEF) level were 164±62 mg/dl, 235±60 mg/dl, 8.5±2 % & 40.1±12.6 score respectively. When compare in both group of MNA, at risk of malnutrition patients show FBG, PPBG, HbA1c & IIEF 177±69mg/dl, 254±84mg/dl, 9.0±2.3% & 39.4±12.3 score respectively. Patients with normal nutritional status levels show FBG, PPBG & HbA1c with significant p value 156±56.3 mg/dl (p-value 0.006), 223.7±71.1mg/dl (p-value 0.001), 8.2±1.7% (p-value 0.003) respectively & IIEF score with non-significant p value, 40.7±12.9  (p-value 0.391). The mean ±SD Body Mass Index (BMI) of the patients was 25.6±4.3kg/m2 in the overweight range.

The patients data show correlation as when MNA score correlate with FBG significantly (r = -0.163, p <0.01), MNA score correlate with PPBG (r = -0.190, p <0.01), MNA correlate with HbA1c (r = -0.179, p <0.01), whereas non-significant correlation was found MNA with IIEF (r = 0.051, p > 0.01) & MNA with age (r = 0.009, p > 0.01).

Conclusion: A high prevalence of malnutrition among adult with diabetes was observed.  Malnutrition was related to blood glucose levels & HbA1c level. So periodic assessment of nutrition of diabetic patients will help in better monitoring & therefore fair control over their blood glucose levels.